Peer Reviewed Structures

HOLD Grainger, R., Heimhelt, M., Brown, C., Berti, P. and Junop, M. (2017) Structure of 2-dehydro-3-deoxyphophoheptonate aldolase (DHAP synthase) in complex with trifluoropyruvate semicarbazone and Mn2+ to 2.5 Å.

HOLD Grainger, R., Heimhelt, M., Brown, C., Berti, P. and Junop, M. (2017) Structure of 2-dehydro-3-deoxyphophoheptonate aldolase (DHAP synthase) in complex with O-(2-fluoroethyl)-oxime to 2.2 Å.

HOLD Grainger, R., Heimhelt, M., Brown, C., Berti, P. and Junop, M. (2017) Structure of 2-dehydro-3-deoxyphophoheptonate aldolase (DHAP synthase) in complex with hydrozone  to 2.0 Å.

HOLD Grainger, R., Heimhelt, M., Brown, C., Berti, P. and Junop, M. (2017) Structure of 2-dehydro-3-deoxyphophoheptonate aldolase (DHAP synthase) in complex with trifluoropyruvate oxime to 2.8 Å resolution.

HOLD Brown, C. and Junop, M. (2017) Structure of full length human XRCC4 to 3.4 Å.

HOLD Brown, C., Gama, S., Balachandran, N., Berti, P. and Junop, M. (2017) Structure of 2-dehydro-3-deoxyphosphoheptonate aldolase (DHAP synthase) in complex with L-tyrosine and Mn2+ to 1.9 Å.

HOLD Brown, C., Gama, S., Balachandran, N., Berti, P. and Junop, M. (2017) Structure of 2-dehydro-3-deoxyphosphoheptonate aldolase (DHAP synthase) in complex with phosphoenolpyruvate (PEP), L-tyrosine and Mn2+ to 2.2 Å.

HOLD Brown, C., Moreau, F. and Junop, M. (2017) Structure of Burkholderia pseudomallei GMHA bound to inhibitor Mut148233 to 2.1 Å.

HOLD Brown, C., Musleh, O., Moreau, F. and Junop, M. (2017) Crystal structure of Escherichia coli GMHA bound to inhibitor Mut148582 to 1.5 Å.

HOLD Brown, C., Moreau, F. and Junop, M. (2017) Structure of apo Burkholderia pseudomallei GMHA in open conformation 1.5 Å.

HOLD Brown, C., Moreau, F. and Junop, M. (2017) Crystal structure of Burkholderia pseudomallei GMHA bound to inhibitor Mut148591 to 1.5 Å.

HOLD Brown, C., Moreau, F. and Junop, M. (2017) Structure of Burkholderia pseudomallei GMHA bound to inhibitor Mut148569 to 2.1 Å. 

HOLD Brown, C., Zlitni, S., Chan, J., Brown, E. and Junop, M. (2017) Crystal structure of Escherichia coli BioA bound to inhibitor MAC13772 to 2.4 Å.

HOLD Lee, T.W. and Junop, M. (2017) Crystal structure of HldC from Burkholderia cenocepacia in complex with ATP.

HOLD Lee, T.W. and Junop, M. (2017) Crystal structure of the Escherichia coli Apo-HldE carboxy-terminal domain.

HOLD Lee, T.W. and Junop, M. (2017) Crystal structure of Burkholderia cenocepacia HldC in complex with product and pyrophosphate.

6BDU Szabla, R., Czerwinski, M. and Junop, M. (2017) Crystal structure of PprA from Deinococcus radiodurans  to 2.0 Å resolution.

6BDB Brown, C., Zhang, K., Laforet, M., McMurrough, T.A., Gloor, G.B., Edgel, D.R. and Junop, M. (2017) Crystal structure of K227Y/D236A I-OnuI mutant endonuclease bound to DNA substrate (A3G) as a pre-cleavage complex.

6BDA Brown, C., Zhang, K., Laforet, M., McMurrough, T.A., Gloor, G.B., Edgel, D.R. and Junop, M. (2017) Crystal structure of wild-type I-OnuI endonuclease bound to cognate DNA substrate as a pre-cleavage complex.

6BD0 Brown, C., Zhang, K., Laforet, M., McMurrough, T.A., Gloor, G.B., Edgel, D.R. and Junop, M. (2017) Crystal structure of K227Y/D236A I-OnuI mutant endonuclease bound to cognate DNA substrate as a pre-cleavage complex.

6BCT Brown, C., Zhang, K., McMurrough, T.A., Gloor, G.B., Edgel, D.R. and Junop, M. (2017) Crystal structure of E184D I-LtrI mutant endonuclease bound to non-cognate DNA substrate ( C4) as a pre-cleavage complex.

6BCN Brown, C., Zhang, K., McMurrough, T.A., Gloor, G.B., Edgel, D.R. and Junop, M. (2017) Crystal structure of E184D I-LtrI mutant endonuclease bound to cognate DNA substrate as a pre-cleavage complex.

6BCI Brown, C., Zhang, K., McMurrough, T.A., Gloor, G.B., Edgel, D.R. and Junop, M. (2017) Crystal structure of wild-type I-LtrI endonuclease bound to non-cognate (C4) DNA substrate as a pre-cleavage complex.

6BCH Brown, C., Zhang, K., McMurrough, T.A., Gloor, G.B., Edgel, D.R. and Junop, M. (2017) Crystal structure of E29D I-LtrI mutant endonuclease in complex with a nicked cognate DNA substrate

6BCG Brown, C., Zhang, K., McMurrough, T.A., Gloor, G.B., Edgel, D.R. and Junop, M. (2017) Crystal structure of A28G I-LtrI mutant endonuclease bound to cognate DNA substrate as a pre-cleavage complex.

6BCF Brown, C., Zhang, K., McMurrough, T.A., Gloor, G.B., Edgel, D.R. and Junop, M. (2017) Crystal structure of G183A I-LtrI mutant endonuclease bound to cognate DNA substrate as a pre-cleavage complex.

6BCE Brown, C., Zhang, K., McMurrough, T.A., Gloor, G.B., Edgel, D.R. and Junop, M. (2017) Crystal structure of wild-type I-LtrI endonuclease bound to cognate DNA substrate as a pre-cleavage complex.

6BDG Brown, C., Zhang, K., Seo, C., Ellis, M.J., Haniford, D.B. and Junop, M. (2017) Crystal structure of Escherichia coli HFQ in spacegroup P6 at 1.93 Å resolution.

5UVR Mok, M., Leighton, T., Burrows, L., Junop, M. and Howell, P. (2017) The core region of PilO from the type IV pilus system of Pseudomonas aeruginosa.

5KUJ Mok, C., Lee, S., Stathopulos, P. and Junop, M. (2016) Human mitochondrial calcium uniporter (residues 72-189) crystal structure with magnesium.

5KUI Mok, C., Lee, S., Stathopulos, P. and Junop, M. (2016) Human mitrochondrial calcium uniporter (residues 72-189) crystal structure with calcium.

5KUG Mok, C., Lee, S., Stathopulos, P. and Junop, M. (2016) Human mitochondrial calcium uniporter (residues 72-189) crystal structure with lithium sulfate.

5KUE Mok, C., Lee, S., Stathopulos, P. and Junop, M. (2016) Human SeMet incorporated I141M/L146M mitochondrial calcium uniporter (residues 72-189) crystal structure.

5EWP Brown, C., Zhang, K., Emery, J., Prusty, D., Wetzel, J., Heincke, D., Gilberger, T. and Junop, M. (2016) ARO (armadillo repeats only protein) from Plasmodium falciparum.

5CKS Berti, P., Balachandran, N. and Junop, M. (2016) Crystal structure of Sialic Acid Synthase (NeuB) from Neisseria meningitis in complex with magnesium and (4S)-2-methyl-2-methyl-2,4-pentanediol.

5C41 Park, J., Lee, T.W., Chakrabarti, J., Gingh, B., Gupta, R and Junop, M. (2016) Crystal structure of human ribokinase in complex with AMPPCP in space group P21 with 4 protomers.

5C40 Park, J., Lee, T.W., Chakrabarti, J., Gingh, B., Gupta, R and Junop, M. (2016) Crystal structure of human ribokinase in complex with AMPPCP in space group P21.

5C3Z Park, J., Lee, T.W., Chakrabarti, J., Gingh, B., Gupta, R and Junop, M. (2016) Crystal structure of human ribokinase in complex with AMPPNP in space group C2.

5C3Y Park, J., Lee, T.W., Chakrabarti, J., Gingh, B., Gupta, R and Junop, M. (2016) Structure of human ribokinase crystallized with AMPPNP.

5BYF Park, J., Lee, T.W., Chakrabarti, J., Gingh, B., Gupta, R and Junop, M. (2016) Crystal structure of human ribokinase in complex with AMP.

5BYE Park, J., Lee, T.W., Chakrabarti, J., Gingh, B., Gupta, R and Junop, M. (2016) Crystal structure of human ribokinase  in space group P212121.

5BYD Park, J., Lee, T.W., Chakrabarti, J., Gingh, B., Gupta, R and Junop, M. (2016) Crystal structure of human ribokinase in space group P21.

5BYC Park, J., Lee, T.W., Chakrabarti, J., Gingh, B., Gupta, R and Junop, M. (2016) Crystal structure of human ribokinase in space group C2.

4NPH Sugiman-Marangos, S., Zhang, K., Cooper, C., Coombes, B. and Junop, M. (2014) Crystal structure of SsaN from Salmonella enterica.

4NOE Sugiman-Marangos, S., Weiss, Y. and Junop, M. (2015) Crystal structure of DdrB from Deinococcus radiodurans in complex with hybrid single and double strand DNA.

4NOA Nguyen, Y., Sugiman-Marangos, S., Bell, S., Burrows, L. and Junop, M. (2014) Crystal structure of Pseudomonas aeruginosa (strain: PA01) type IV minor pilin PilE

4MBQ Nguyen, Y., Zhang, K., Daniel-Ivad, M., Sugiman-Marangos, Burrows, L. and Junop, M. (2014) TRP3 of FimV from Pseudomonas aeruginosa (strain: PA01).

4MAL Nguyen, Y., Sugiman-Marangos, Bell, S., Burrows, L. and Junop, M. (2014) Crystal structure of Pseudomonas aeruginosa (strain: PA01) TRP3 of FimV from Pseudomonas aeruginosa.

4IQZ Sugiman-Marangos, S. and Junop, M. (2013) The crystal structure of a large insert in RNA polymerase (RpoC) subunit from Escherichia coli.

4IPV Nguyen, Y., Sugiman-Marangos, Bell, S., Giltner, C., Harvey, H., S., Burrows, L. and Junop, M. (2014) Crystal structure of Pseudomonas aeruginosa (strain: PA01) type IV minor pilin FimU in space group P65.

4IPU Nguyen, Y., Sugiman-Marangos, Bell, S., Giltner, C., Harvey, H., S., Burrows, L. and Junop, M. (2014) Crystal structure of Pseudomonas aeruginosa (strain: PA01) type IV minor pilin FimU in space group P21.

4HQB Sugiman-Marangos, S. and Junop, M. (2013) Crystal structure of DdrB from Deinococcus radiodurans bound to ssDNA

4F6L Mok, M., Tandon, P., Wyatt, M., Magarvey, N. and Junop, M. (2011) Crystal structure of the terminal reductase domain from the Aureusimine biosynthetic cluster.

4F6C Mok, M., Tandon, P., Wyatt, M., Magarvey, N. and Junop, M. (2011) Crystal structure of the terminal transferase-reductase domains from the Aureusimine biosynthetic cluster.

4E8Z Lee, T.W. and Junop, M. (2013) Crystal structure of HldA Burkholderia cenocepacia in complex with an ATP-competitive inhibitor.

4E8Y  Lee, T.W. and Junop, M. (2013) Crystal structure of Burkholderia cenocepacia HldA in complex with an ATP-competitive inhibitor.

4E8W Lee, T.W. and Junop, M. (2013) Crystal structure of HldA from Burkholderia cenocepacia in complex with an ATP-competitive inhibitor

4E84 Lee, T.W. and Junop, M. (2013) Crystal structure of Apo-HldA from Burkholderia cenocepacia.

4DZ1 Mok, M., Junop, M. (2012) Crystal structure of DalS, an ATP binding cassette transporter for D-alanine from Salmonella enterica.

4DRW Lee, T-W., Rezvanpour, A., Shaw, G. and Junop, M. (2012) Crystal structure of a heteropentameric complex between S100A10, annexin A2 and AHNAK.

3Q9D Stone, C.B., Sugiman-Marangos, S.N., Junop, M.S., Mahony, J.B. (2011) Crystal structure of Cpn0803 from C. pneumoniae.

3RWR Andres, S.N., Junop, M.S. (2011) Crystal structure of the human XRCC4-XLF complex.

3KDV/4EXW Sugiman-Marangos, S.N., Junop, M.S. (2010) Crystal structure of DNA damage response B (DdrB) from Deinococcus geothermalis.

3L1U Sugiman-Marangos, S.N., Junop, M.S. (2010) Crystal structure of Calcium-bound GmhB from E. coli.

3L1V Sugiman-Marangos, S.N., Junop, M.S. (2010) Crystal structure of GmhB from E. coli in complex with calcium and phosphate.

3ISS Jackson, S.G., Zhang, F., Chindemi, P., Junop, M.S., Berti, P.J. (2009) Crystal structure of enolpyruvyl-UDP-GlcNAc synthase (MurA):UDP-N-actylmuramic acid:phosphite from Escherichia coli.

3JYZ Nguyen, Y., Jackson, S.G., Aidoo, F., Junop, M.S., Burrows, L.K. (2009) Crystal structure of Pseudomonas aeruginosa (strain: Pa110594) typeIV pilin in space group P412121.

3JZZ Nguyen, Y., Jackson, S.G., Aidoo, F., Junop, M.S., Burrows, L.K. (2009) Crystal structure of Pseudomonas aeruginosa (strain: Pa110594) typeIV pilin in space group P212121.

3EPU Zhang, K., Andres, S.N., Hannemann, M., Coombes, B., Junop, M. (2009) Crystal structure of STM2138, a novel virulence chaperone in Salmonella.

3II6 Meesala, S., Junop, M.S. (2009) Structure of human Xrcc4 in complex with the tandem BRCT domains of DNA LigaseIV.

3E35 Gao, B., Gupta, R., Sugiman-Marangos, S., Junop, M.S. (2009) Actinobacteria-specific protein of unknown function SCO1997.

3CM4 Rosanally, A., Morrison, E., Berti, P., Junop, M.S. (2008) Crystal structure of metal-free sialic acid synthase (NeuB) from neisseria meningitidis in complex with malate.

2ZDR Morrison, E., Rosanally, A., Berti, P. and Junop, M.S. (2007) Crystal Structure of sialic acid synthase (NeuB) from neisseria meningitidis in complex with magnesium and (4S)-2-methyl-2,4-pentanediol.

2R9A Andres, S.N. and Junop, M.S. (2007) Crystal Structure of human non-homologous end joining DNA repair protein Cernunnos/XLF.

2OPT Willems, A.R. and Junop, M.S. (2007) Crystal Structure of Apo ActR from Streptomyces coelicolor.

3B6A Willems, A.R. and Junop, M.S. (2007) Crystal Structure of Streptomyces coelicolor ActR in complex with actinorodin .

3B6C Willems, A.R. and Junop, M.S. (2007) Crystal Structure of (S)DNPA-bound ActR from Streptomyces coelicolor.

2I5F Jackson, S.G. and Junop, M.S. (2006) Crystal structure of human pleckstrin C-terminal domain in complex with D-myo-Ins(1,2,3,5,6)P5.

2I2W DeLeon, G., Blakely, K., Wright, G., Junop, M. (2006) Crystal structure of Escherichia coli phosphoheptose isomerase.

2I5C Jackson, S.G. and Junop, M.S. (2006) Crystal structure of the C-terminal PH domain of pleckstrin in complex with D-myo-Ins(1,2,3,4,5)P.

2I22 Zhang, K., DeLeon, G., Blakely, K., Wright, G., Junop, M. (2006) Crystal structure of Escherichia coli phosphoheptose isomerase in complex with reaction substrate sedoheptulose 7-phosphate.

2HW2 Baysarowich, J., Wright, G., Junop, M.S. (2006) Crystal structure of Rifampin ADP-ribosyl transferase in complex with Rifampin.

2GQN Summerfield, R., Zhang, K., and Junop, M.S. (2006) Cystathionine ß-lyase (cbl) from escherichia coli in complex with n-hydrazinocarbonylmethyl-2-nitro-benzamide . 

2GMW Zhang, K.,  DeLeon, G.,  Wright, G.D.,   Junop, M.S. (2006) Crystal Structure of D,D-heptose 1.7-bisphosphate phosphatase from E. Coli .

2FQ6 Summerfield, R.,  Zhang, K., and Junop, M.S. (2006) Cystathionine ß-lyase from escherichia coli in complex with n-hydrazinocarbonylmethyl-2-trifluoromethyl-benzamide. 

2ANQ Summerfield, R., Jackson , S.G., Sulek, M., and Junop, M.S. (2005) Crystal structure of E. coli dihydrofolate reductase in complex with NADPH and 1,4-bis-{[N-(1-imino-1guanidino-methyl)]sulfanylmethyl}- 3,6-dimethyl-benzene.

2ANO Summerfield, R., Jackson , S.G., Sulek, M., and Junop, M.S. (2005) Crystal structure of E. coli dihydrofolate reductase in complex with NADPH and 1-{[N-(1-imino-guanidino-methyl)]sulfanylmethyl}- 3-trifluoromethyl-benzene.

1ZMO Jackson , S.G., Zhang, K., Summerfield, R., and Junop, M.S. (2005) Crystal structure of the carboxyl terminal PH domain of human pleckstrin to 2.1 angstroms.

1H7U Guarne, A., Junop, M.S. and Yang, W. (2001) Human DNA mismatch repair protein PMS2 in complex with ATP?S.

1H7S Guarne, A., Junop, M.S. and Yang, W. (2001) N-terminal 40 KDa fragment of human mismatch repair protein PMS2.

1FW6 Junop, M.S., Obmolova, G., Rausch, K., Hsieh. and Yang, W. (2001) Crystal structure of DNA mismatch repair protein MutS in complex with ADP and a mismatch containing DNA substrate.

1EA6 Guarne, A., Junop, M.S. and Yang, W. (2001) N-terminal 40Kda fragment of human mismatch repair protein PMS2 in complex with ADP.